Knockdown of Menin Affects pre-mRNA Processing

Knockdown of Menin Affects pre-mRNA Processing and Promoter Fidelity at the Interferon-gamma Inducible IRF1 Gene
-Auriemma L, et al. Epigenetics & Chromatin 2012, 5:2 doi:10.1186/1756-8935-5-2.

• MEN1 contributes to STAT1-activated gene expression in a novel manner that includes defining the transcription start site and RNA processing.
• IRF1 heteronuclear transcripts become enriched in MEN1-depleted cells.