What Extent of Pancreatic Resection Do Patients with MEN-1 Require?

What Extent of Pancreatic Resection Do Patients with MEN-1 Require?
-C. D. Adkisson, et al.
JOP. J Pancreas (Online) 2012 Jul 10; 13(4):402-408.

• "In patients with MEN-1 and pancreatic endocrine tumors, preoperative workup underestimates extent of disease and total pancreatectomy should be considered for complete tumor removal."
  

Dopamine And Sleep Regulation

Dopamine And Sleep Regulation

• "These results are interesting as they demonstrate a mechanism in which dopamine, normally increased at times of stimulation, can directly inhibit production and release of a molecule, melatonin, that induces drowsiness and prepares the body for sleep..."

Chronic Inflammation and Gastroenteropancreatic Neuroendocrine Tumors

The Association of Chronic Inflammation and Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)
-Maja Cigrovski Berković, Davorka Herman Mahečić, Vedran Tomašić, Davor Hrabar and Vanja Zjačić-Rotkvić (2012).
The Association of Chronic Inflammation and Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs), Neuroendocrine Tumor, Dr. Anthony Lowell (Ed.), ISBN: 978-953-51-0653-1, InTech,
Available from: http://www.intechopen.com/books/neuroendocrine-tumor/the-association-of-chronic-inflammation-and-gastroenteropancreatic-neuroendocrine-tumors-gep-nets-

Vitamin D and cancer

Vitamin D and cancer
-Vuolo L, Di Somma C, Faggiano A and Colao A (2012) Vitamin D and cancer.
Front. Endocrin. 3:58. doi: 10.3389/fendo.2012.00058

Genome-Wide Characterization of Menin-Dependent H3K4me3 Reveals a Specific Role for Menin

Genome-Wide Characterization of Menin-Dependent H3K4me3 Reveals a Specific Role for Menin in the Regulation of Genes Implicated in MEN1-Like Tumors
-S Agarwal, R Jothi
PLoS ONE 7(5): e37952. doi:10.1371/journal.pone.0037952

The Genetics of Pituitary Adenomas

The Genetics of Pituitary Adenomas
-Monica Fedele, Giovanna Maria Pierantoni and Alfredo Fusco (2011). The Genetics of Pituitary Adenomas, Contemporary Aspects of Endocrinology, Dr. Evanthia Diamanti-Kandarakis (Ed.), ISBN: 978-953-307-357-6, InTech, Available from: http://www.intechopen.com/books/contemporary-aspects-of-endocrinology/the-genetics-of-pituitary-adenomas

Prolactin Receptor in Primary Hyperparathyroidism – Expression, Functionality and Clinical Correlations

Prolactin Receptor in Primary Hyperparathyroidism – Expression, Functionality and Clinical Correlations
-Haglund F, et al. PLoS ONE May 2012, Volume 7, Issue 5, e36448.

• "...the prolactin receptor is highly abundant in human parathyroid tissues"
• "...PRLr isoforms expression and PRLr subcellular localisation are altered in parathyroid tumours."
• "Responsiveness of PRLr to physiological levels of prolactin was observed in the form of increased PTH secretion and altered gene transcription with significant increase of RIG-I like receptor, JAK-STAT and Type II interferon signalling pathways."
• "These data suggest a role of the prolactin receptor in parathyroid adenomas."