MEN1 intragenic deletions appear common in sporadic primary hyperparathyroidism

MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism

-M Alvelos, et al.
European Journal of Endocrinology, October 23, 2012 EJE-12-0327

MEN Syndrome and M.E.N. 1: Parathyroid, Pituitary, Pancreas, Thyroid Tumors and MEN type 1 Syndrome - Disorders of the Parathyroid, Pituitary, and Pancreas

MEN Syndrome and M.E.N. 1: Parathyroid, Pituitary, Pancreas, Thyroid Tumors and MEN type 1 Syndrome - Disorders of the Parathyroid, Pituitary, and Pancreas

An overview of MEN1, its treatment, and what patients can expect.

By James Norman MD, FACS, FACE
Norman Parathyroid Center
http://www.parathyroid.com/Parathyroid-Surgeon.htm

Prolactin produced in the breast may play a role in breast cancer

http://www.medicalnewstoday.com/releases/250906.php

• "...prolactin has long been thought to play a role in human breast cancer, however this has typically been assumed to be due to circulating prolactin produced by the pituitary. Since the PI3K-Akt signaling pathway is commonly activated in human cancers, this new finding suggests the important possibility that prolactin produced by the breast itself may play a role in breast cancer."
  
• "Since the PI3K-Akt pathway is one of the most commonly activated oncogenic pathways in human cancer, its identification as an upstream regulator of prolactin production in the mammary gland has intriguing potential implications for understanding the pathology of human breast cancer and as well as improving its treatment..."
  

-Medical News Today, October 2, 2012