September 27, 2013

Research shows how medicine for the brain can be absorbed through the nose

Research shows how medicine for the brain can be absorbed through the nose
-University of Southern Denmark. "Research shows how medicine for the brain can be absorbed through the nose." Medical News Today. MediLexicon, Intl., 27 Sep. 2013. Web. 27 Sep. 2013.

Editor's notes:
There may be a wonderful use for nasal administration in the treatment of medically resistant pituitary prolactinomas.  These are commonly treated medically by oral administration of the dopamine agonists cabergoline (CAB) or bromocriptine (BRO).  But in some patients normalization of PRL (prolactin) levels is not achieved with even unusually high doses of CAB or BRO. If CAB or BRO can be delivered effectively to the brain via nasal administration, it may be possible to produce higher therapeutic levels of the drug at the pituitary tumor while avoiding the undesired increased exposure to other systems which may be affected: such as the kidneys, pancreas, and immune system.

Cref: Dopamine -Wikipedia

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